p63 Antikörper (Tumor Protein P63) (AA 651-680)

Details for Product anti-TP63 Antibody No. ABIN657886, Anbieter: Anmelden zum Anzeigen
Antigen
  • TP63
  • tp63
  • TP73L
  • AI528772
  • CCT
  • Cct1
  • Ccta
  • TRic
  • Tcp-1
  • Tp63
  • c-cpn
  • p63
  • AI462811
  • Ket
  • P51/P63
  • P63
  • P73l
  • Trp53rp1
  • AIS
  • B(p51A)
  • B(p51B)
  • EEC3
  • KET
  • LMS
  • NBP
  • OFC8
  • RHS
  • SHFM4
  • TP53CP
  • TP53L
  • p40
  • p51
  • p53CP
  • p73H
  • p73L
  • Tp73l
  • Trp63
  • DNp63
  • id:ibd3516
  • tp73l
  • wu:fc89f04
  • wu:fk85h07
  • wu:fk88b02
  • Xp63
  • ket
  • np63
  • tp73l-A
  • trp63
  • TRP63
  • tumor protein p63
  • tumor protein p73-like
  • t-complex protein 1
  • transformation related protein 63
  • tumor protein p63-like
  • TP63
  • tp63
  • LOC100227936
  • LOC100393670
  • LOC100433100
  • LOC100480840
  • LOC100496308
  • LOC100512967
  • LOC100545037
  • LOC100577122
  • LOC100594205
  • LOC100611345
  • LOC100624851
  • LOC100648488
  • Tcp1
  • Trp63
  • Tp63
  • LOC100355881
Epitop
AA 651-680, C-Term
14
7
7
4
3
2
2
1
1
1
1
1
1
Reaktivität
Human
79
16
15
1
Wirt
Kaninchen
40
35
4
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser p63 Antikörper ist unkonjugiert
1
1
1
1
1
1
Applikation
Western Blotting (WB)
50
42
16
14
12
6
6
3
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This TP63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 AA from the C-terminal region of human TP63.
Klon RB30257
Isotyp Ig
Spezifität This TP63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 650-680 amino acids from the C-terminal region of human TP63.
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung TP63 (TP63 Antibody Abstract)
Hintergrund This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
Synonyms: Tumor protein 63,8626,KET, P63, P73H, P73L, TP73L
Molekulargewicht 76785 DA
Gen-ID 8626
NCBI Accession NP_003713, NP_001108451, NP_001108452
UniProt Q9H3D4
Forschungsgebiet Ubiquitin-related antibodies, Apoptosis/Necrosis, Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Applikationshinweise WB = 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung TP63 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Protein P63 (TP63) (AA 651-680), (C-Term) antibody (ABIN657886) TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysa...
Produkt verwendet in: Zamudio, Wang, Chung, Wolosin: "Inhibition of TGF? cell signaling for limbal explant culture in serumless, defined xeno-free conditions." in: Experimental eye research, Vol. 145, pp. 48-57, 2015 (PubMed).

Allgemeine Veröffentlichungen Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: "Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations." in: Nature genetics, Vol. 42, Issue 10, pp. 893-6, 2010 (PubMed).

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