ARHGDIB Antikörper (C-Term)

Produktnummer ABIN657665

Produktdetails anti-ARHGDIB Antikörper

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Bindungsspezifität: AA 160-188, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.

Klon: RB33730

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ARHGDIB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-ARHGDIB Antikörper (ABIN657665)

Huang, Zhang, Jiang, Chen, Liu, Ge, Li, Dang, Wen, Liu, Lu, Tang: "RhoGDI? Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation." in: The Journal of biological chemistry, Vol. 290, Issue 17, pp. 11119-29, (2015) (PubMed).

Details zu ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: ARHGDIB (ARHGDIB Produkte)

Synonyme: ARHGDIB antikoerper, zgc:65966 antikoerper, arhgdib antikoerper, MGC69067 antikoerper, gdia2 antikoerper, rhodgi-2 antikoerper, rhodgi2 antikoerper, D4 antikoerper, GDIA2 antikoerper, GDID4 antikoerper, LYGDI antikoerper, Ly-GDI antikoerper, RAP1GN1 antikoerper, RhoGDI2 antikoerper, Gdid4 antikoerper, Rho GDP dissociation inhibitor (GDI) gamma antikoerper, Rho GDP dissociation inhibitor (GDI) beta S homeolog antikoerper, Rho GDP dissociation inhibitor beta antikoerper, Rho GDP dissociation inhibitor (GDI) beta antikoerper, Rho, GDP dissociation inhibitor (GDI) beta antikoerper, arhgdig antikoerper, arhgdib.S antikoerper, ARHGDIB antikoerper, arhgdib antikoerper, Arhgdib antikoerper

Hintergrund: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).

Molekulargewicht: 22988

Gen-ID: 397

NCBI Accession: NP_001166

UniProt: P52566

Pathways: Caspase Kaskade in der Apoptose