NLRP6 Antikörper (N-Term)

Produktnummer ABIN657452

Produktdetails anti-NLRP6 Antikörper

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Bindungsspezifität: AA 168-197, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NLRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the N-terminal region of human NLRP6.

Klon: RB33587

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: NLRP6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Andere Bezeichnung: NLRP6 (NLRP6 Produkte)

Synonyme: NLRP6 antikoerper, NALP6 antikoerper, AVR antikoerper, CLR11.4 antikoerper, NAVR antikoerper, NAVR/AVR antikoerper, PAN3 antikoerper, PYPAF5 antikoerper, AI504961 antikoerper, Avr antikoerper, Nalp6 antikoerper, Navr antikoerper, Navr/Avr antikoerper, Pypaf5 antikoerper, NLR family pyrin domain containing 6 antikoerper, NLR family, pyrin domain containing 6 antikoerper, NLRP6 antikoerper, Nlrp6 antikoerper

Hintergrund: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).

Molekulargewicht: 98768

Gen-ID: 171389

NCBI Accession: NP_001263629, NP_612202

UniProt: P59044

Pathways: Inflammasome