STARD4 Antikörper (N-Term)

Produktnummer ABIN656728

Produktdetails anti-STARD4 Antikörper

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Bindungsspezifität: AA 8-37, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STARD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STARD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human STARD4.

Klon: RB32027

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: STARD4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Andere Bezeichnung: STARD4 (STARD4 Produkte)

Synonyme: 4632419C16Rik antikoerper, 9030213J02Rik antikoerper, AA517649 antikoerper, AW324468 antikoerper, StAR related lipid transfer domain containing 4 antikoerper, StAR-related lipid transfer (START) domain containing 4 antikoerper, STARD4 antikoerper, Stard4 antikoerper

Hintergrund: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).

Molekulargewicht: 23517

Gen-ID: 134429

NCBI Accession: NP_631903

UniProt: Q96DR4