EIF3CL Antikörper (N-Term)
EIF3CL
Reaktivität: Human
WB, FACS, IHC (p)
Wirt: Kaninchen
Polyclonal
RB32067
unconjugated
-
- Target Alle EIF3CL Produkte
- EIF3CL (Eukaryotic Translation Initiation Factor 3, Subunit C-Like (EIF3CL))
- Bindungsspezifität
- AA 127-155, N-Term
- Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser EIF3CL Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B, M, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This EIF3CL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the N-terminal region of human EIF3CL.
- Klon
- RB32067
- Isotyp
- Ig Fraction
-
-
- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- EIF3CL Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
-
- Target
- EIF3CL (Eukaryotic Translation Initiation Factor 3, Subunit C-Like (EIF3CL))
- Andere Bezeichnung
- EIF3CL (EIF3CL Produkte)
- Synonyme
- eukaryotic translation initiation factor 3 subunit C like antikoerper, EIF3CL antikoerper
- Hintergrund
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Molekulargewicht
- 105344
- Gen-ID
- 8663
- NCBI Accession
- NP_001032897, NP_001186071, NP_001254503, NP_003743
- UniProt
- Q99613
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