DVL1 Antikörper (Dishevelled, Dsh Homolog 1 (Drosophila)) (AA 442-470)

Details for Product anti-DVL1 Antibody No. ABIN656260, Anbieter: Anmelden zum Anzeigen
Antigen
  • Xdsh
  • dsh1
  • dvl-1
  • DVL
  • DVL1L1
  • DVL1P1
  • DSH
  • DVL-22
  • DVL1
  • DVL4
  • Dvl
  • mKIAA4029
  • DVL-1
  • dvl1
  • dvl2l
  • dishevelled segment polarity protein 1
  • dishevelled segment polarity protein 1 pseudogene 1
  • dishevelled, dsh homolog 1 (Drosophila)
  • dishevelled, dsh homolog 1b (Drosophila)
  • dvl1
  • Dvl1
  • DVL1
  • DVL1P1
  • dvl1b
Alternativen
anti-Human DVL1 Antikörper für ELISA
Epitop
AA 442-470, Center
15
14
10
9
9
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human
58
41
28
16
8
5
4
3
3
2
2
2
1
1
1
Wirt
Kaninchen
56
22
3
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser DVL1 Antikörper ist unkonjugiert
7
7
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
45
17
15
13
8
6
1
1
Optionen
Hersteller
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Immunogen This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 AA from the Central region of human DVL1.
Klon RB31716
Isotyp Ig
Spezifität This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from the Central region of human DVL1.
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung DVL1 (DVL1 Antibody Abstract)
Hintergrund DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Synonyms: DVL1,Segment polarity protein dishevelled homolog DVL-1,
Pathways: Wnt signaling pathway, Melanogenesis, Basal cell carcinoma
Molekulargewicht 75187 Da
Gen-ID 1855
UniProt O14640
Forschungsgebiet Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.46 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
 image for anti-DVL1 Antikörper (Dishevelled, Dsh Homolog 1 (Drosophila)) (AA 442-470) (ABIN656260) Confocal immunofluorescent analysis of DVL1 Antibody (Center) (ABIN656260) with HepG2...
Allgemeine Veröffentlichungen Varelas, Miller, Sopko, Song, Gregorieff, Fellouse, Sakuma, Pawson, Hunziker, McNeill, Wrana, Attisano: "The Hippo pathway regulates Wnt/beta-catenin signaling." in: Developmental cell, Vol. 18, Issue 4, pp. 579-91, 2010 (PubMed).