KDM3B Antikörper (AA 869-897)
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- Target Alle KDM3B Antikörper anzeigen
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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Bindungsspezifität
- AA 869-897
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM3B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Homologie
- M
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This JHDM2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 869-897 amino acids from the Central region of human JHDM2b.
- Klon
- RB14344
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product KDM3B Primärantikörper
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anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 307-448) antibody
KDM3B Reaktivität: Human WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1059-1283) antibodyKDM3B Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1601-1761) antibodyKDM3B Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1328-1358), (C-Term) antibodyKDM3B Reaktivität: Maus WB, FACS Wirt: Kaninchen Polyclonal RB14629 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 25-57), (N-Term) antibodyKDM3B Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB10782 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (pSer291) antibodyKDM3B Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB22220 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (C-Term) antibodyKDM3B Reaktivität: Maus WB, ELISA Wirt: Maus Monoclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (C-Term) antibodyKDM3B Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1-759) antibodyKDM3B Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (Internal Region) antibodyKDM3B Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
- Andere Bezeichnung
- JHDM2b (KDM3B Produkte)
- Hintergrund
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
- Molekulargewicht
- 191581
- Gen-ID
- 51780
- NCBI Accession
- NP_057688
- UniProt
- Q7LBC6
- Pathways
- Warburg Effekt
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