TNFSF15 Antikörper (AA 148-175)

Produktnummer ABIN655822

Produktdetails anti-TNFSF15 Antikörper

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Bindungsspezifität: AA 148-175

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFSF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-175 amino acids from the Central region of human TNFSF15.

Klon: RB21818

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu TNFSF15

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Andere Bezeichnung: TNFSF15 (TNFSF15 Produkte)

Synonyme: TTPAL antikoerper, TL1 antikoerper, TL1A antikoerper, VEGI antikoerper, VEGI192A antikoerper, Tl1 antikoerper, Tl1a antikoerper, Vegi antikoerper, tumor necrosis factor superfamily member 15 antikoerper, TNF superfamily member 15 antikoerper, tumor necrosis factor (ligand) superfamily, member 15 antikoerper, TNFSF15 antikoerper, Tnfsf15 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq].

Molekulargewicht: 28087

Gen-ID: 9966

NCBI Accession: NP_001191273, NP_005109

UniProt: O95150

Pathways: Positive Regulation of Endopeptidase Activity, Autophagie