Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SP1 Antikörper (C-Term)

SP1 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB17350 unconjugated
Produktnummer ABIN655398
  • Target Alle SP1 Antikörper anzeigen
    SP1 (Sp1 Transcription Factor (SP1))
    Bindungsspezifität
    • 20
    • 13
    • 12
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 677-707, C-Term
    Reaktivität
    • 95
    • 64
    • 43
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 96
    • 13
    • 3
    Kaninchen
    Klonalität
    • 89
    • 23
    Polyklonal
    Konjugat
    • 67
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SP1 Antikörper ist unkonjugiert
    Applikation
    • 90
    • 46
    • 46
    • 38
    • 21
    • 17
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human SP1.
    Klon
    RB17350
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Zhang, Wang, Qin, Liu, Sun, Liu, Kuang, Jiang, Zhang: "cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression." in: PLoS ONE, Vol. 8, Issue 12, pp. e83097, (2014) (PubMed).

  • Target
    SP1 (Sp1 Transcription Factor (SP1))
    Andere Bezeichnung
    SP1 (SP1 Produkte)
    Synonyme
    fc18h09 antikoerper, zgc:85950 antikoerper, wu:fc18h09 antikoerper, SP1 antikoerper, 1110003E12Rik antikoerper, AA450830 antikoerper, AI845540 antikoerper, Sp1-1 antikoerper, sp1 transcription factor antikoerper, Sp1 transcription factor antikoerper, Sp1 transcription factor L homeolog antikoerper, trans-acting transcription factor 1 antikoerper, sp1 antikoerper, SP1 antikoerper, Sp1 antikoerper, sp1.L antikoerper
    Hintergrund
    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
    Molekulargewicht
    80693
    Gen-ID
    6667
    NCBI Accession
    NP_001238754, NP_003100, NP_612482
    UniProt
    P08047
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
Sie sind hier:
Kundenservice