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Retinoblastoma 1 Antikörper (C-Term)

RB1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20715 unconjugated
Produktnummer ABIN652516
  • Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
    Retinoblastoma 1 (RB1)
    Bindungsspezifität
    • 35
    • 34
    • 29
    • 24
    • 24
    • 22
    • 20
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 858-886, C-Term
    Reaktivität
    • 299
    • 120
    • 101
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 250
    • 52
    Kaninchen
    Klonalität
    • 237
    • 65
    Polyklonal
    Konjugat
    • 151
    • 19
    • 17
    • 16
    • 11
    • 11
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
    Applikation
    • 225
    • 132
    • 113
    • 80
    • 79
    • 42
    • 41
    • 36
    • 28
    • 20
    • 18
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1.
    Klon
    RB20715
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RB1 Primärantikörper
  • Applikationshinweise
    WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Retinoblastoma 1 (RB1)
    Andere Bezeichnung
    RB1 (RB1 Produkte)
    Synonyme
    OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper
    Hintergrund
    RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
    Molekulargewicht
    106159
    Gen-ID
    5925
    NCBI Accession
    NP_000312
    UniProt
    P06400
    Pathways
    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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