PLA2G4A Antikörper (AA 513-541)

Produktnummer ABIN652449

Produktdetails anti-PLA2G4A Antikörper

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Bindungsspezifität: AA 513-541

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: C, Zf, Hs, M, Rb, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.

Klon: RB21320

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PLA2G4A

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Andere Bezeichnung: PLA2G4A (PLA2G4A Produkte)

Synonyme: PLA2G4 antikoerper, cPLA2-alpha antikoerper, Pla2c antikoerper, Pla2g4 antikoerper, cPLA2 antikoerper, pla2g4 antikoerper, CPLA2 antikoerper, PLA2G4A antikoerper, PLA2 antikoerper, PLA2G1B antikoerper, cPLA2alpha antikoerper, pla2g4a antikoerper, si:dkey-97o5.1 antikoerper, phospholipase A2 group IVA antikoerper, phospholipase A2 group IVA L homeolog antikoerper, phospholipase A2, group IVA (cytosolic, calcium-dependent) antikoerper, phospholipase A2, group IVAb (cytosolic, calcium-dependent) antikoerper, PLA2G4A antikoerper, Pla2g4a antikoerper, pla2g4a.L antikoerper, pla2g4ab antikoerper

Hintergrund: PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Molekulargewicht: 85239

Gen-ID: 5321

NCBI Accession: NP_077734

UniProt: P47712

Pathways: Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling