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GLS2 Antikörper (AA 498-524)

GLS2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB20072 unconjugated
Produktnummer ABIN652216
  • Target Alle GLS2 Antikörper anzeigen
    GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 498-524
    Reaktivität
    • 28
    • 21
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 40
    • 4
    Kaninchen
    Klonalität
    • 40
    • 4
    Polyklonal
    Konjugat
    • 16
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLS2 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 22
    • 16
    • 13
    • 13
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GLS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-524 amino acids of human GLS2.
    Klon
    RB20072
    Isotyp
    IgG
    Top Product
    Discover our top product GLS2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P-Leica: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).

  • Target
    GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))
    Andere Bezeichnung
    GLS2 (GLS2 Produkte)
    Synonyme
    si:ch211-216k22.10 antikoerper, GA antikoerper, GLS antikoerper, LGA antikoerper, hLGA antikoerper, A330074B06Rik antikoerper, AI195532 antikoerper, Lga antikoerper, Ga antikoerper, glutaminase 2 antikoerper, glutaminase 2a (liver, mitochondrial) antikoerper, glutaminase 2 (liver, mitochondrial) antikoerper, glsA2 antikoerper, LOAG_03311 antikoerper, gls2a antikoerper, GLS2 antikoerper, Gls2 antikoerper
    Hintergrund
    The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq].
    Molekulargewicht
    66323
    Gen-ID
    27165
    NCBI Accession
    NP_001267727, NP_037399
    UniProt
    Q9UI32
    Pathways
    Dicarboxylic Acid Transport, Warburg Effekt
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