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Metabotropic Glutamate Receptor 3 Antikörper (C-Term)

GRM3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB4623 unconjugated
Produktnummer ABIN652205
  • Target Alle Metabotropic Glutamate Receptor 3 (GRM3) Antikörper anzeigen
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Bindungsspezifität
    • 16
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 828-857, C-Term
    Reaktivität
    • 40
    • 31
    • 14
    • 11
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 54
    • 2
    • 1
    Kaninchen
    Klonalität
    • 54
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Metabotropic Glutamate Receptor 3 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 20
    • 17
    • 10
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Pr
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Metabotropic Glutamate Receptor 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-857 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 3.
    Klon
    RB4623
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GRM3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
    Andere Bezeichnung
    Metabotropic Glutamate Receptor 3 (GPRC1C) (GRM3 Produkte)
    Synonyme
    GLUR3 antikoerper, GPRC1C antikoerper, MGLUR3 antikoerper, mGlu3 antikoerper, 0710001G23Rik antikoerper, Gprc1c antikoerper, mGluR3 antikoerper, glutamate metabotropic receptor 3 antikoerper, glutamate receptor, metabotropic 3 antikoerper, GRM3 antikoerper, Grm3 antikoerper
    Hintergrund
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 (also known as GPRC1C) while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM3 is mediated by a G-protein that inhibits adenylate cyclase activity.
    Molekulargewicht
    98879
    Gen-ID
    2913
    NCBI Accession
    NP_000831
    UniProt
    Q14832
    Pathways
    cAMP Metabolic Process, Synaptic Membrane
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