Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) Antikörper

Details zu Produkt Nr. ABIN651855, Anbieter: Anmelden zum Anzeigen
Antigen
  • PACAP
  • grf
  • pac1
  • pacapr
  • pacapri
  • Pacap
  • adcyap1
  • GRF-PACAP
  • zgc:103760
  • xx:af217251
  • pacap
  • ADCYAP1
  • adenylate cyclase activating polypeptide 1
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
  • adenylate cyclase activating polypeptide 1a
  • adenylate cyclase activating polypeptide 1 (pituitary)
  • ADCYAP1
  • adcyap1r1
  • Adcyap1
  • adcyap1a
  • adcyap1
Epitop
AA 148-176, C-Term
25
18
15
9
6
6
5
3
2
1
1
1
1
Reaktivität
Human
107
49
30
24
3
3
3
1
1
1
1
1
Wirt
Kaninchen
93
16
9
Klonalität (Klon)
Polyklonal ()
Konjugat
Unkonjugiert
7
5
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
61
51
30
23
14
13
8
8
3
3
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This ADCYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 AA from the C-terminal region of human ADCYAP1.
Klon RB21605
Isotyp Ig Fraction
Spezifität This ADCYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from the C-terminal region of human ADCYAP1.
Homologie Mouse (Murine),Pig (Porcine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung ADCYAP1 (ADCYAP1 Antibody Abstract)
Hintergrund ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
Synonyms: Pituitary adenylate cyclase-activating polypeptide,ADCYAP1,
Molekulargewicht 18835 DA
Gen-ID 116
NCBI Accession NP_001093203
UniProt P18509
Forschungsgebiet Signaling, Cell Signaling, Protein Modifications, Cell Structure
Pathways Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Activity, cAMP Metabolic Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Regulation of G-Protein Coupled Receptor Protein Signaling
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.33 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) western blot analysis in 293 cell line lysates...
Immunohistochemistry (IHC) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) immunohistochemistry analysis in formalin fixe...
Flow Cytometry (FACS) image for anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 148-176), (C-Term) antibody (ABIN651855) ADCYAP1 Antibody (C-term) (ABIN651855) flow cytometric analysis of 293 cells (right h...
Allgemeine Veröffentlichungen Hosoya, Kimura, Ogi, Ohkubo, Miyamoto, Kugoh, Shimizu, Onda, Oshimura, Arimura: "Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene." in: Biochimica et biophysica acta, Vol. 1129, Issue 2, pp. 199-206, 1992 (PubMed).

Ohkubo, Kimura, Ogi, Okazaki, Hosoya, Onda, Miyata, Arimura, Fujino: "Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide." in: DNA and cell biology, Vol. 11, Issue 1, pp. 21-30, 1992 (PubMed).

Kimura, Ohkubo, Ogi, Hosoya, Itoh, Onda, Miyata, Jiang, Dahl, Stibbs: "A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs." in: Biochemical and biophysical research communications, Vol. 166, Issue 1, pp. 81-9, 1990 (PubMed).

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