V-Rel Reticuloendotheliosis Viral Oncogene Homolog A, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 3, P65 (RELA) Antikörper

Antigen: V-Rel Reticuloendotheliosis Viral Oncogene Homolog A, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 3, P65 (RELA)

Synonyme: p50, KBF1, p105, EBP-1, MGC54151, NFKB-p50, NF-kappaB, NFKB-p105, NF-kappa-B, DKFZp686C01211, NF-kB, NF-KB1, Xrel1, nfkb3, xrela, MGC69459, NFKB1, kbf1, ebp-1, MGC86262, nfkb-p50, nf-kappaB, nfkb-p105, nf-kappa-b, RELA, p65, NFKB3, MGC131774

Wirt: Kaninchen

Applikation: ELISA, Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN640748

Produktbeschreibung

Produktmerkmale: Rabbit Anti-NFkB p65

Weitere Bezeichnung: NFkB p65

Immunogen: Synthetic peptide corresponding to residues surrounding S536 of human NFkB p65 protein.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Isotyp: IgG  (Passende Sekundärantikörper)

Spezifität: DS-PB-02845 recognizes the p65 subunit of nuclear factor kappa-B (NFkB), otherwise known as RelA. NFkB is a heterodimeric DNA binding protein which was originally identified consisting of p65 and p50 (NFkB1) subunits. Research has led to the discovery of other subunits, including p52 (NFkB2), cRel, and RelB. NFkB is ubiquitously expressed, and functions as a second messenger which upon activation leads to the transcription of a number of genes. NFkB is activated by a number of agents, including pro-inflammatory cytokines and bacterial lipopolysaccharide, and is essential for the maturation of T cells and regulation of their survival and activation.

Synonyme: p50, KBF1, p105, EBP-1, MGC54151, NFKB-p50, NF-kappaB, NFKB-p105, NF-kappa-B, DKFZp686C01211, NF-kB, NF-KB1, Xrel1, nfkb3, xrela, MGC69459, NFKB1, kbf1, ebp-1, MGC86262, nfkb-p50, nf-kappaB, nfkb-p105, nf-kappa-b, RELA, p65, NFKB3, MGC131774

Anwendungen

Konzentration: IgG concentration 1.0 mg/ml

Reinigung: Purified

Buffer: Phosphate buffered saline pH7.2

Konservierungsmittel: 0.01% Sodium Azide (NaN 3 )

Lagerung: Store at +4 ° C or at -20 ° C if preferred.

Forschungsgebiet: Artherosklerose, Alzheimer-Krankheit (Morbus Alzheimer), Apoptose/Nekrose, Transkriptionsfaktoren, Angeborene Immunität

Beschränkungen: Nur für Forschungszwecke einsetzbar