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Histone H1 Antikörper

Antigen

Histone H1

Synonyme H1c, H1.2, H1f2, His1a, H1var1, MGC107646, 0610008C09Rik, LOC692942, HISTONE H1, HON4
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen ELISA, Western Blot (WB), Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunfluoreszenz (IF)
Produktnummer ABIN640557
Menge 0.2 mg  (IgG concentration 1.0 mg/ml)  (Varianten)
Preis 459,62 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Produktmerkmale Mouse Anti-Human Histone H1
Immunogen Nuclei from myeloid leukamia biopsy cells.
Isotyp IgG2a  (Passende Sekundärantikörper)
Spezifität DS-MB-01531 recognizes histone H1. The histone proteins serve as a structural scaffold for the organization of nuclear DNA into chromatin. In eukaryotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that assemble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber. In blots of rat brain homogenate a duplet is observed at 27-29 kDa consistent with Histone H1. Speckled staining is observed in the nucleus of normal and malignant cells.

Anwendungen

Konzentration IgG concentration 1.0 mg/ml
Reinigung Purified
Buffer Phosphate buffered saline
Konservierungsmittel 0.09% Sodium Azide
Lagerung 18 months from date of dispatch. Store at 4 ° C or at -20 ° C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. Avoid repeated freezing and thawing as this may denature the antibody
Forschungsgebiet Chromatin und nukleäre Signaltransduktion, DNS/RNS, Transkriptionsfaktoren
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Histone H1", Typ "Antikörper" finden
Wirte Kaninchen (29), Maus (20), Schaf (6), Huhn (5)
Reaktivitäten Human (46), Maus (22), Rind (Kuh) (21), Ratte (Rattus) (18), Hund (16), Pferd (16), Kaninchen (16), Schwein (15), Säugetiere (1)
Applikationen Immunfluoreszenz (IF) (39), Western Blot (WB) (34), Durchflusszytometrie (FACS) (18), ELISA (16), Immunhistochemie (Paraffinschnitte) (IHC (p)) (15), Immunpräzipitation (IP) (11), Immunhistochemie (IHC) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Enzyme Immunoassay (EIA) (4), Immunzytochemie (ICC) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Chromatin-Immunopräzipitation (ChiP) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope Acetyl-Lys25 (1), pThr17 (1)