Vitamin D Receptor (VDR) Antikörper

Antigen: Vitamin D Receptor (VDR)

Synonyme: vdr-A, xVDR, VDR, NR1I1, NR1I1-B, gb:dq017633, vdr-b, Ci-VDR-b, LOC100008907, LOC100136219, LOC100136371, vdr0, vdralpha, vdrbeta, DKFZp469H1213, LOC100221284, Nr1i1

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN640145

Produktbeschreibung

Produktmerkmale: Goat Anti-Human Vitamin D Receptor

Weitere Bezeichnung: Vitamin D Receptor

Immunogen: Peptide sequence CGNQDYKYRVSD corresponding to the internal region of Vitamin D receptor (NP_000367.1).

Kreuzreaktivität: Ratte (Rattus), Maus, Hund

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Synonyms: NR1I1

Spezifität: DS-PB-02327 recognizes human vitamin D nuclear hormone receptor (VDR) a 48 kDa member of the trans-acting transcriptional regulatory factors. On binding vitamin D, VDR regulates the expression of hormone sensitive genes. The main downstream target of VDR is involved in bone mineral metabolism although VDR is also involved in immune response and cancer metabolic pathways. VDR also acts as a receptor for secondary bile acid lithocholic acid. Additionally, signalling and oncogenic activity of beta-catenin signalling has been shown to be repressed by VDR.

Anwendungen

Konzentration: IgG concentration 0.5 mg/ml

Reinigung: Purified

Buffer: TRIS buffered saline pH7.3

Konservierungsmittel: 0.02% Sodium Azide (NaN 3 ), 0.5% Bovine Serum Albumin

Lagerung: Store at +4 ° C or at -20 ° C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch

Forschungsgebiet: Krebs, Transkriptionsfaktoren, Vitamine

Beschränkungen: Nur für Forschungszwecke einsetzbar