17-beta Estradiol Antikörper

Antigen: 17-beta Estradiol

Wirt: Maus

Applikation: ELISA

Produktnummer: ABIN638762

Produktbeschreibung

Produktmerkmale: Mouse Anti-17-beta-Estradiol

Weitere Bezeichnung: 17-beta-Estradiol

Wiederherstellung: Supplied as 200 µg of purified antibody. It is reconstituted with 200 µl of sterile PBS. Its final concentration is 1.0 mg/ml. Please avoid freeze-thaw cycles.

Isotyp: IgG2b  (Passende Sekundärantikörper)

Beschreibung: 17 beta Estradiol is a potent mammalian estrogenic hormone that is produced in the ovaries (by the granulosa cells), in the placenta, testis and possibly the adrenal cortex. The hormone is synthesized enzymatically from acetate, cholesterol, progesterone and testosterone. In addition to anatomic and physiological regulation of reproduction and secondary sex characteristics, it also influences activities such as bone growth, brain development and maturation and the intracellular concentrations of calcium and certain second messenger molecules. Research demonstrates salutary effects of 17 beta estradiol following trauma-hemorrhage on different cell types. 17 beta estradiol also induces improved circulation through relaxation of the aorta and has an anti-apoptotic effect on endothelial cells. 17 beta estradiol is also implicated in the attenuation of H2O2-induced apoptosis via ER-dependent activation of caspase-9 and - 3 in rat endothelial cells through mitochondria.

Spezifität: DS-MB-02565 is specific for 17-beta estradiol, a mammalian estrogenic hormone, produced in the ovaries, placenta and testis that has a role in normal sexual development and the regulation of the menstrual cycle. DS-MB-02565 exhibits negligible cross reactivity with estriol and testosterone.

Anwendungen

Reinigung: Purified

Lagerung: Store at -20 ° C, if not intended for use within a month. Keep it at 4 ° C and minimize freezing and thawing when use.

Forschungsgebiet: Hormone

Beschränkungen: Nur für Forschungszwecke einsetzbar