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CD19 Antikörper (PE)

CD19 Reaktivität: Human FACS Wirt: Maus Monoclonal 4G7 PE
Produktnummer ABIN638442
  • Target Alle CD19 Antikörper anzeigen
    CD19 (CD19 Molecule (CD19))
    Reaktivität
    • 304
    • 180
    • 48
    • 30
    • 19
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 184
    • 141
    • 63
    • 4
    Maus
    Klonalität
    • 260
    • 128
    • 2
    Monoklonal
    Konjugat
    • 118
    • 25
    • 21
    • 21
    • 18
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD19 Antikörper ist konjugiert mit PE
    Applikation
    • 273
    • 121
    • 75
    • 66
    • 61
    • 43
    • 23
    • 21
    • 17
    • 14
    • 14
    • 10
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 4G7 recognizes an extracellular epitope of human CD19.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human CCL (chronic lymphocytic leukemia) cells
    Klon
    4G7
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD19 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Andersen, Pedersen, Woetmann, Villingshøj, Stockhausen, Odum, Poulsen: "EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 2, pp. 342-9, (2007) (PubMed).

    Martino, Tonelli, Montemurro, Franzoni, Marino, Fazzina, Pession: "Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23)." in: Oncology reports, Vol. 15, Issue 1, pp. 207-11, (2005) (PubMed).

    Köller, Zwölfer, Steiner, Smolen, Scheinecker: "Phenotypic and functional deficiencies of monocyte-derived dendritic cells in systemic lupus erythematosus (SLE) patients." in: International immunology, Vol. 16, Issue 11, pp. 1595-604, (2004) (PubMed).

    Porcellini, Vallanti, Nozza, Poli, Lazzarin, Tambussi, Siccardi, Grassi: "Improved thymopoietic potential in aviremic HIV infected individuals treated with HAART by intermittent IL-2 administration." in: AIDS, Vol. 17, Issue 11, pp. 1621-30, (2003) (PubMed).

    Basu, Lynne, Ruiz, Aballa, Ferrell, Brackett: "Cytofluorographic identification of activated T-cell subpopulations in the semen of men with spinal cord injuries." in: Journal of andrology, Vol. 23, Issue 4, pp. 551-6, (2002) (PubMed).

    Dubois, Massacrier, Caux: "Selective attraction of naive and memory B cells by dendritic cells." in: Journal of leukocyte biology, Vol. 70, Issue 4, pp. 633-41, (2001) (PubMed).

    Stockmeyer, Dechant, van Egmond, Tutt, Sundarapandiyan, Graziano, Repp, Kalden, Gramatzki, Glennie, van de Winkel, Valerius: "Triggering Fc alpha-receptor I (CD89) recruits neutrophils as effector cells for CD20-directed antibody therapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 10, pp. 5954-61, (2000) (PubMed).

    Muench, Roncarolo, Namikawa: "Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver." in: Blood, Vol. 89, Issue 4, pp. 1364-75, (1997) (PubMed).

  • Target
    CD19 (CD19 Molecule (CD19))
    Andere Bezeichnung
    CD19 (CD19 Produkte)
    Synonyme
    B4 antikoerper, CVID3 antikoerper, AW495831 antikoerper, CD19 antikoerper, CD19 molecule antikoerper, CD19 antigen antikoerper, CD19 antikoerper, Cd19 antikoerper
    Hintergrund
    CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3
    Gen-ID
    930
    UniProt
    P15391
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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