HERC5 Antikörper (Middle Region)

Produktnummer ABIN634098

Produktdetails anti-HERC5 Antikörper

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: HERC5 antibody was raised against the middle region of HERC5

Aufreinigung: Affinity purified

Immunogen: HERC5 antibody was raised using the middle region of HERC5 corresponding to a region with amino acids FHPEELKDVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTL

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

HERC5 Blocking Peptide, catalog no. 33R-2921, is also available for use as a blocking control in assays to test for specificity of this HERC5 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HERC5 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu HERC5

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Andere Bezeichnung: HERC5 (HERC5 Produkte)

Synonyme: HERC5 antikoerper, CEB1 antikoerper, CEBP1 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antikoerper, hect domain and RLD 5 antikoerper, HERC5 antikoerper

Hintergrund: This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Molekulargewicht: 117 kDa (MW of target protein)