MAGED1 Antikörper (C-Term)

Produktnummer ABIN616057

Produktdetails anti-MAGED1 Antikörper

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-EAEARAEARN RMGIGDE

Spezifität: This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse, Rat

Aufreinigung: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide with sequence derived from Mouse Melanoma-associated antigen D1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Andere Bezeichnung: MAGE-D1 (MAGED1 Produkte)

Synonyme: MAGED1 antikoerper, DLXIN-1 antikoerper, NRAGE antikoerper, 2810433C11Rik antikoerper, 5430405L04Rik antikoerper, DXBwg1492e antikoerper, Dlixin antikoerper, Dlxin-1 antikoerper, Dlxin1 antikoerper, MAGE-D1 antikoerper, mFLJ00163 antikoerper, Nrage antikoerper, MAGE family member D1 antikoerper, melanoma antigen family D, 1 antikoerper, melanoma antigen, family D, 1 antikoerper, MAGED1 antikoerper, Maged1 antikoerper

Hintergrund: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.Synonyms: MAGE tumor antigen CCF, MAGED1, Melanoma-associated antigen D1, NRAGE, Neurotrophin receptor-interacting MAGE homolog

Molekulargewicht: 95 kDa

Gen-ID: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signalübertragung