EIF2S2 Antikörper (pSer2)

Produktnummer ABIN616039

Produktdetails anti-EIF2S2 Antikörper

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Bindungsspezifität: pSer2

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2S2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: M-S(p)-G-D-E

Spezifität: This antibody detects endogenous levels of eIF2β only when phosphorylated at serine 2.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide sequence around phosphorylation site of serine 2 derived from eIF2beta.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu EIF2S2

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Andere Bezeichnung: EIF2B / EIF2S2 (EIF2S2 Produkte)

Synonyme: EIF2 antikoerper, EIF2B antikoerper, EIF2beta antikoerper, PPP1R67 antikoerper, eIF-2-beta antikoerper, 2810026E11Rik antikoerper, 38kDa antikoerper, AA408636 antikoerper, AA571381 antikoerper, AA986487 antikoerper, AW822225 antikoerper, D2Ertd303e antikoerper, zgc:77084 antikoerper, wu:fc26g03 antikoerper, wu:fu10f07 antikoerper, MGC130959 antikoerper, DDBDRAFT_0205105 antikoerper, DDBDRAFT_0234112 antikoerper, DDB_0205105 antikoerper, DDB_0234112 antikoerper, AO090005001412 antikoerper, eukaryotic translation initiation factor 2 subunit beta antikoerper, eukaryotic translation initiation factor 2, subunit 2 (beta) antikoerper, eukaryotic translation initiation factor 2, subunit 2 beta antikoerper, eukaryotic translation initiation factor 2 subunit beta L homeolog antikoerper, eIF-3 beta antikoerper, hypothetical protein antikoerper, eukaryotic translation initiation factor 2 subunit 2 antikoerper, EIF2S2 antikoerper, Eif2s2 antikoerper, eif2s2 antikoerper, eif2s2.L antikoerper, eIF2s2 antikoerper, TP02_0678 antikoerper, EDI_093670 antikoerper, AOR_1_2450174 antikoerper, MGYG_05853 antikoerper, PGTG_10708 antikoerper, LOC101111733 antikoerper

Hintergrund: EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.Synonyms: Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, eIF2-beta

Molekulargewicht: 38 kDa

Gen-ID: 8894

NCBI Accession: NP_003899

UniProt: P20042