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KIR2DL4/CD158d Antikörper

KIR2DL4 Reaktivität: Human WB, FACS, IP, Func, IF Wirt: Maus Monoclonal mAb#33 unconjugated
Produktnummer ABIN614805
  • Target Alle KIR2DL4/CD158d (KIR2DL4) Antikörper anzeigen
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    Reaktivität
    • 55
    • 1
    • 1
    Human
    Wirt
    • 37
    • 18
    Maus
    Klonalität
    • 37
    • 18
    Monoklonal
    Konjugat
    • 20
    • 8
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIR2DL4/CD158d Antikörper ist unkonjugiert
    Applikation
    • 47
    • 28
    • 17
    • 14
    • 13
    • 13
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunofluorescence (IF)
    Spezifität
    This Monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein-A Affinity Chromatography
    Immunogen
    NK3.3 cells and KIR2DL4-Ig fusion protein
    Klon
    MAb#33
    Isotyp
    IgG1
    Top Product
    Discover our top product KIR2DL4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    KIR2DL4/CD158d (KIR2DL4) (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
    Andere Bezeichnung
    CD158d / KIR2DL4 (KIR2DL4 Produkte)
    Synonyme
    G9P antikoerper, CD158D antikoerper, KIR103 antikoerper, KIR103AS antikoerper, KIR2DL4 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 antikoerper, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 antikoerper, KIR2DL4 antikoerper
    Hintergrund
    CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.Synonyms: CD158 antigen-like family member D, G9P, KIR103AS, Killer cell immunoglobulin-like receptor 2DL4, Killer cell inhibitory receptor 103AS, MHC class I NK cell receptor KIR103AS
    Gen-ID
    3805
    NCBI Accession
    NP_001074239
    UniProt
    Q99706
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