TNNI1 Antikörper

Produktnummer ABIN614371

Produktdetails anti-TNNI1 Antikörper

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNNI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes Troponin I Skeletal (TNNI). Less than 0.05 % cross-reactivity with Cardiac TNI

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography.

Immunogen: Mouse Skeletal muscle Troponin I.

Klon: 12F10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TNNI1

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Abstract: TNNI1 Produkte

Synonyme: ANM antikoerper, NEM5 antikoerper, STNT antikoerper, TNT antikoerper, TNTS antikoerper, TnI-S4 antikoerper, SSTNI antikoerper, TNN1 antikoerper, 2700018B22Rik antikoerper, AI747285 antikoerper, ssTnI antikoerper, AW146156 antikoerper, Tnt antikoerper, sTnT antikoerper, ssTnT antikoerper, Fang2 antikoerper, tnTs antikoerper, troponin 1 antikoerper, zgc:86895 antikoerper, troponin T1, slow skeletal type antikoerper, troponin I1, slow skeletal type antikoerper, troponin I, skeletal, slow 1 antikoerper, troponin T1, skeletal, slow antikoerper, troponin I1, slow skeletal type S homeolog antikoerper, troponin I type 1 (skeletal, slow) antikoerper, troponin I4b, tandem duplicate 2 antikoerper, TNNT1 antikoerper, TNNI1 antikoerper, Tnni1 antikoerper, Tnnt1 antikoerper, tnni1.S antikoerper, tnni4b.2 antikoerper

Hintergrund: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. This antibody reacts with subunit I of the troponin complex in human myocardium, where it is the only troponin I isotype present. It does not cross-react with troponin I of skeletal muscle cells.Synonyms: TNNI1

Gen-ID: 7135

NCBI Accession: NP_003272

UniProt: P19237