Alpha-methylacyl-CoA racemase Antikörper

Antigen: Alpha-methylacyl-CoA racemase

Klonalität: Monoklonal (2F3-C11-B12)

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN614201

Produktbeschreibung

Gen-ID: AMACR

Swiss-Prot: Q9UHK6

Immunogen: Recombinant fragment, corresponding to amino acids 138-319aa of human AMACR (C-terminus).

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 2F3-C11-B12

Beschreibung: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.

Spezifität: Mouse monoclonal to AMACR

Anwendungen

Applikationshinweise: ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000

Konzentration: 1. 000mg/ml

Reinheit: > 90%

Reinigung: Protein G-Sepharose affinity purified

Buffer: Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.

Lagerung: Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°

Forschungsgebiet: Krebs, Signaltransduktion, Chromatin und nukleäre Signaltransduktion, Zell-/Gewebemarker

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

AMACR (C-terminus) antibody at 1/1000 dilution, Lane 1: Rat Liver lysate 40ug/Lane, Predicted band size: 42kDa, Observed band size: 42kDa