ADAM8 Antikörper (AA 70-119)

Produktnummer ABIN6746715

Produktdetails anti-ADAM8 Antikörper

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Bindungsspezifität: AA 70-119

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Human ADAM8

Homologie: Percent identity by BLAST analysis: Human (100%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa70-119 of human ADAM8 (NP_001100). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%), Mouse (78%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-ADAM8 Antikörper (ABIN6746715)

Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).

Li, Sorensen, Brooke, Urness, Davis, Taylor, Boak, Wendel: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).

Bellón, Corbí, Lastres, Calés, Cebrián, Vera, Cheifetz, Massague, Letarte, Bernabéu: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).

Gougos, Letarte: "Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8361-4, (1990) (PubMed).

Details zu ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Andere Bezeichnung: ADAM8 (ADAM8 Produkte)

Synonyme: CD156 antikoerper, MS2 antikoerper, CD156a antikoerper, E430039A18Rik antikoerper, adam8 antikoerper, reprolysin antikoerper, si:zc217g15.7 antikoerper, zgc:64059 antikoerper, ADAM8 antikoerper, RGD1566394 antikoerper, ADAM metallopeptidase domain 8 antikoerper, a disintegrin and metalloproteinase domain 8 antikoerper, a disintegrin and metallopeptidase domain 8 antikoerper, ADAM metallopeptidase domain 8a antikoerper, ADAM8 antikoerper, LOC100304737 antikoerper, Adam8 antikoerper, adam8a antikoerper, adam8 antikoerper

Hintergrund: Name/Gene ID: ADAM8
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM8, ADAM metallopeptidase domain 8, Cell surface antigen MS2, ADAM 8, MS2, CD156, CD156a antigen

Gen-ID: 101

NCBI Accession: NP_001100

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase