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PAR1 Antikörper (AA 267-316)

F2R Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6746560
  • Target Alle PAR1 (F2R) Antikörper anzeigen
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 267-316
    Reaktivität
    • 68
    • 24
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus, Schwein, Kaninchen
    Wirt
    • 61
    • 7
    • 2
    Kaninchen
    Klonalität
    • 64
    • 6
    Polyklonal
    Konjugat
    • 39
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAR1 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 36
    • 13
    • 13
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Human F2R / Thrombin Receptor
    Homologie
    Percent identity by BLAST analysis: Mouse, Rat (100%) Dog (92%) Pig (85%) Rabbit (84%).
    Aufreinigung
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa267-316 of human F2R (P25116, NP_001983). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Mouse, Rat (100%), Gibbon, Baboon, Monkey, Galago, Marmoset, Hamster, Dog, Horse (92%), Pig (85%), Rabbit (84%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product F2R Primärantikörper
  • Applikationshinweise
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Distilled water
    Konzentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Gradin, Larsson, Marklund, Gullberg: "Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells." in: The Journal of cell biology, Vol. 140, Issue 1, pp. 131-41, (1998) (PubMed).

    Horwitz, Shen, He, Dittmar, Neef, Chen, Schubart: "The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8129-32, (1997) (PubMed).

    Larsson, Marklund, Gradin, Brattsand, Gullberg: "Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis." in: Molecular and cellular biology, Vol. 17, Issue 9, pp. 5530-9, (1997) (PubMed).

  • Target
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Andere Bezeichnung
    F2R / Thrombin Receptor / PAR1 (F2R Produkte)
    Synonyme
    CF2R antikoerper, HTR antikoerper, PAR-1 antikoerper, PAR1 antikoerper, TR antikoerper, Par1 antikoerper, TRGPC antikoerper, AI482343 antikoerper, Cf2r antikoerper, ThrR antikoerper, Par-1 antikoerper, f2r-a antikoerper, par1 antikoerper, coagulation factor II thrombin receptor antikoerper, coagulation factor II (thrombin) receptor antikoerper, coagulation factor 2 (thrombin) receptor L homeolog antikoerper, F2R antikoerper, F2r antikoerper, f2r.L antikoerper
    Hintergrund
    Name/Gene ID: F2R
    Subfamily: Proteinase-activated
    Family: GPCR

    Synonyms: F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1
    Gen-ID
    2149
    NCBI Accession
    NP_001983
    UniProt
    P25116
    Pathways
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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