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PDE8A Antikörper (AA 551-600)

PDE8A Reaktivität: Human, Ratte, Affe, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6746531
  • Target Alle PDE8A Antikörper anzeigen
    PDE8A (phosphodiesterase 8A (PDE8A))
    Bindungsspezifität
    • 17
    • 13
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-600
    Reaktivität
    • 52
    • 11
    • 10
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Affe, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen
    Wirt
    • 48
    • 4
    Kaninchen
    Klonalität
    • 49
    • 3
    Polyklonal
    Konjugat
    • 25
    • 7
    • 7
    • 5
    • 4
    • 4
    Dieser PDE8A Antikörper ist unkonjugiert
    Applikation
    • 35
    • 33
    • 32
    • 8
    • 8
    • 7
    • 6
    • 6
    • 1
    Western Blotting (WB)
    Spezifität
    Human PDE8A
    Homologie
    Percent identity by BLAST analysis: Human, Dog, Bovine, Rabbit, Horse, Guinea pig (100%) Mouse, Rat, Chicken, Zebrafish (92%).
    Aufreinigung
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa551-600 of human PDE8A (O60658, NP_002596). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Rat, Dog, Bovine, Rabbit, Horse, Guinea pig (100%), Mouse, Elephant, Pig, Opossum, Turkey, Zebra finch, Chicken, Xenopus, Zebrafish (92%), Marmoset, Bat (85%), Platypus, Drosophila (84%), Bloom alga (83%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product PDE8A Primärantikörper
  • Applikationshinweise
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Distilled water
    Konzentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Shahan, Sorenson, Simpson, Kefalides, Lewis: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, (2000) (PubMed).

    Yang, Malek, Desiderio: "An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20832-40, (1995) (PubMed).

    Aoki, Isselbacher, Pillai: "Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10606-9, (1994) (PubMed).

    Vetrie, Vorechovský, Sideras, Holland, Davies, Flinter, Hammarström, Kinnon, Levinsky, Bobrow: "The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases." in: Nature, Vol. 361, Issue 6409, pp. 226-33, (1993) (PubMed).

  • Target
    PDE8A (phosphodiesterase 8A (PDE8A))
    Andere Bezeichnung
    PDE8A (PDE8A Produkte)
    Synonyme
    PDE8A antikoerper, Pde8a antikoerper, HsT19550 antikoerper, AI551852 antikoerper, Pde8 antikoerper, RNPDE8A antikoerper, phosphodiesterase 8A antikoerper, PDE8A antikoerper, Pde8a antikoerper, pde8a antikoerper
    Hintergrund
    Name/Gene ID: PDE8A
    Subfamily: PDE - cAMP-specific, high affinity
    Family: Phosphodiesterase

    Synonyms: PDE8A, Phosphodiesterase 8A, HsT19550
    Gen-ID
    5151
    NCBI Accession
    NP_002596
    UniProt
    O60658
    Pathways
    cAMP Metabolic Process
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