IRGC Antikörper (AA 73-122)

Produktnummer ABIN6746505

Produktdetails anti-IRGC Antikörper

Target: IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

Bindungsspezifität: AA 73-122

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRGC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Mouse IRGC

Homologie: Percent identity by BLAST analysis: Mouse (100%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-IRGC Antikörper (ABIN6746505)

Bolton, Anthony, Perry: "Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).

Fanning, Jameson, Jesaitis, Anderson: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, (1998) (PubMed).

Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." in: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, (1996) (PubMed).

Details zu IRGC

Target: IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

Andere Bezeichnung: IRGC1 / CINEMA (IRGC Produkte)

Synonyme: IFGGE antikoerper, CINEMA antikoerper, IRGC1 antikoerper, Iigp5 antikoerper, R30953_1 antikoerper, Ifgge antikoerper, Irgc1 antikoerper, RGD1311107 antikoerper, F630044M05Rik antikoerper, Gm1102 antikoerper, Gm474 antikoerper, Irgc antikoerper, immunity related GTPase cinema antikoerper, interferon-inducible GTPase 5-like antikoerper, immunity-related GTPase family, cinema antikoerper, immunity-related GTPase family, cinema 1 antikoerper, IRGC antikoerper, LOC476445 antikoerper, Irgc antikoerper, Irgc1 antikoerper

Hintergrund: Name/Gene ID: IRGC

Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1

Gen-ID: 56269

NCBI Accession: NP_950178

UniProt: Q6NXR0