TGF-beta Antikörper
(1 reference)-
- Target Alle TGF-beta (TGFb) Antikörper anzeigen
- TGF-beta (TGFb)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TGF-beta Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Neutralization (Neut), ELISA, Functional Studies (Func), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Marke
- IHC-plus™
- Spezifität
- Recognizes both human platelet-derived and recombinant TGF-beta.
- Aufreinigung
- Protein G purified
- Immunogen
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TGF-b from human platelets.
Type of Immunogen: Purified protein - Klon
- TB21
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product TGFb Primärantikörper
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anti-TGF-beta (TGFb) (AA 301-350) antibody
TGFb Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb Reaktivität: Human, Maus, Ratte, Kaninchen, Säugetier WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Hamster, Affe ELISA, Func, D, ELISA (Capture) Wirt: Maus Monoclonal TGFB-510 unconjugated
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- Applikationshinweise
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Approved: ELISA, Func, IHC, IHC-Fr, IHC-P (10 μg/mL), Neut, WB
Usage: Suitable for use in Western Blot, ELISA, Neutralization and Immunohistochemistry. Neutralization: Neutralizes TGF-beta activity in vitro in an inhibition assay of CCL/64 cell growth and the growth promoting action of TGF-beta in the NRK-49F colony forming assay. The effect of microinjection of this antibody into one blastomere of two cell stage Xenopus embryos indicated that it was able to neutralize effectively the bioactivity of TGF-beta in vivo. Immunohistochemistry (formalin-fixed, paraffin-embedded, frozen): 1:1000. Has been used to demonstrate TGF-beta in ovine ovarian tissue and human breast carcinoma. As a consequence of the intense staining of the erythrocytes it is possible to locate a single cell within the ovarian stroma making it useful in locating very fine capillary networks within tissue. Western Blot: 5-20 ng/mL will allow visualization of 100 ng/lane of TGF-beta. Recognizes the dimeric (25kD) and monomeric (12.5kD) forms of TGF-beta under both non-reducing and reducing conditions respectively. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.0.
- Handhabung
- avoid freeze thaw cycles.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).
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: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).
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- Target
- TGF-beta (TGFb)
- Andere Bezeichnung
- TGF-beta (TGFb Produkte)
- Synonyme
- CED antikoerper, DPD1 antikoerper, LAP antikoerper, TGFB antikoerper, TGFbeta antikoerper, TGF-beta antikoerper, TGF-BETA-1 antikoerper, TGF-beta1 antikoerper, TGFbeta1 antikoerper, Tgfb antikoerper, Tgfb-1 antikoerper, transforming growth factor beta 1 antikoerper, transforming growth factor beta-1 antikoerper, transforming growth factor, beta 1 antikoerper, TGFB1 antikoerper, Tgfb1 antikoerper
- Pathways
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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