ELAVL1 Antikörper

Produktnummer ABIN577055

Produktdetails anti-ELAVL1 Antikörper

Target: ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ELAVL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Spezifität: Greater than 95%

Aufreinigung: Purified IgG

Reinheit: > 98 %

Immunogen: Synthetic Peptide

Klon: 19F12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Works on IHC at 1/2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml

Buffer: PBS /glycerol

Lagerung: -20 °C

Referenzen für anti-ELAVL1 Antikörper (ABIN577055)

Ni, Zhou, Song, Chen, Wang, Du, Zhang: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." in: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).

Li, Lu, Dai, Torregroza, Hla, Evans: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." in: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).

Chang, Lu, Li, Hsieh, Xiong, Ghosh, Evans, Elemento, Hla: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).

García-Domínguez, Morello, Cisneros, Kontoyiannis, Frade: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." in: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).

Details zu ELAVL1

Target: ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))

Andere Bezeichnung: HuR (ELAVL1 Produkte)

Synonyme: ELAV1 antikoerper, HUR antikoerper, Hua antikoerper, MelG antikoerper, HuR antikoerper, 2410055N02Rik antikoerper, W91709 antikoerper, elra antikoerper, fa25f08 antikoerper, fb59a02 antikoerper, fc60g02 antikoerper, hua antikoerper, wu:fa25f08 antikoerper, wu:fb59a02 antikoerper, wu:fc60g02 antikoerper, zHuA antikoerper, Elavl1 antikoerper, Xel-1 antikoerper, elav1 antikoerper, elrA antikoerper, hur antikoerper, melg antikoerper, p36 antikoerper, ElrA antikoerper, elavl1 antikoerper, elavl1-a antikoerper, elavl1-b antikoerper, ELAV like RNA binding protein 1 antikoerper, ELAV-like protein 1 antikoerper, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) antikoerper, ELAV like RNA binding protein 1a antikoerper, ELAV like RNA binding protein 1 L homeolog antikoerper, ELAV like RNA binding protein 1 S homeolog antikoerper, ELAVL1 antikoerper, Elavl1 antikoerper, elav1 antikoerper, elavl1a antikoerper, elavl1.L antikoerper, elavl1.S antikoerper

Hintergrund: HuR (also called Elavl-1 or HuA) is a protein that binds to specific AU-rich elements in a mRNA and thereby upregulates its expression. The protein contains three RRM type RNA binding domains. The first and second RNA binding domains interact with the AU-rich element. HuR is a member of a family of proteins called the elav-like proteins. The other members, HuD, HuC, and HEL-N1 are predominantly expressed in neurons. Monoclonal 19F12 was designed by CLONEGENE and was generated against a unique HuR peptide and does not react with HuD, HuC, or Hel-N1.

Pathways: AMPK Signaling