MUC1 Glycoprotein Antikörper

Antigen: MUC1 Glycoprotein

Klonalität: Monoklonal (M2F1)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN573206

Produktbeschreibung

Produktmerkmale: MAb to Muc1

Immunogen: High molecular weight (>300kDa) glycoprotein from human milk-fat globule molecule.

Isotyp: IgG  (Passende Sekundärantikörper)

Klon: M2F1

Spezifität: Efficiently recognizes underglycosylated and natural MUC1 protein isolated from human milk by affinity chromatography. Does not cross-react with normal serum proteins and human tissues of nonepithelial origin. Binds with high efficiency with an epitope within the VNTR tandem repeat peptide region of MUC1.

Sensitivität: Affinity constant: >1 x 10 8

Anwendungen

Applikationshinweise: Can be used for immunohistochemical staining of paraffin and frozen sections. Can be used for staining of paraffin-embedded tissue sections fixed in neutral-buffered formalin and is compatible with commonly used histological fixatives. Can be used in the form of enzyme conjugate for development in ELISA sandwich assays of under-glycosylated tumor-associated MUC1 mucins in human serum. May be used in conjunction with M86240M and M86410M specific to unglycosylated VNTR region of MUC1 as the capture reagent.

Konzentration: 5.7mg/ml (OD280nm, E 0.1% = 1.4)

Reinigung: >90% pure (SDS-PAGE). Protein A chromatography

Buffer: PBS, pH 7.4. Preservative: 0.1% Sodium azide.

Lagerung: Store at 2–8°C. Warning This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Beschränkungen: Nur für Forschungszwecke einsetzbar