Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD34 Antikörper

CD34 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal 581 unconjugated
Produktnummer ABIN571353
  • Target Alle CD34 Antikörper anzeigen
    CD34
    Reaktivität
    • 312
    • 115
    • 105
    • 33
    • 19
    • 18
    • 17
    • 17
    • 16
    • 16
    • 9
    • 6
    • 5
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 182
    • 145
    • 22
    • 6
    • 4
    Maus
    Klonalität
    • 240
    • 116
    • 2
    Monoklonal
    Konjugat
    • 131
    • 29
    • 28
    • 23
    • 18
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD34 Antikörper ist unkonjugiert
    Applikation
    • 241
    • 208
    • 92
    • 67
    • 62
    • 53
    • 39
    • 37
    • 34
    • 28
    • 23
    • 20
    • 13
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The mouse monoclonal antibody 581 reacts with an extracellular epitope of CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease.
    Keine Kreuzreaktivität
    Schaf
    Kreuzreaktivität (Details)
    Human, Non-Human Primates
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Klon
    581
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD34 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Goardon, Nikolousis, Sternberg, Chu, Craddock, Richardson, Benson, Drayson, Standen, Vyas, Freeman: "Reduced CD38 expression on CD34+ cells as a diagnostic test in myelodysplastic syndromes." in: Haematologica, Vol. 94, Issue 8, pp. 1160-3, (2009) (PubMed).

    Ninos, Jefferies, Cogle, Kerr: "The thrombopoietin receptor, c-Mpl, is a selective surface marker for human hematopoietic stem cells." in: Journal of translational medicine, Vol. 4, pp. 9, (2006) (PubMed).

    Ono, Sharma, Smith, Burnett, Aurelian: "CD34+ cells in the peripheral blood transport herpes simplex virus DNA fragments to the skin of patients with erythema multiforme (HAEM)." in: The Journal of investigative dermatology, Vol. 124, Issue 6, pp. 1215-24, (2005) (PubMed).

    Kato, Ando, Nakamura, Muguruma, Sato, Yabe, Yabe, Hattori, Yasuda, Hotta: "Absence of a CD34- hematopoietic precursor population in recipients of CD34+ stem cell transplantation." in: Bone marrow transplantation, Vol. 28, Issue 6, pp. 587-95, (2001) (PubMed).

    Felschow, McVeigh, Hoehn, Civin, Fackler: "The adapter protein CrkL associates with CD34." in: Blood, Vol. 97, Issue 12, pp. 3768-75, (2001) (PubMed).

    Ando, Nakamura, Chargui, Matsuzawa, Tsuji, Kato, Hotta: "Extensive generation of human cord blood CD34(+) stem cells from Lin(-)CD34(-) cells in a long-term in vitro system." in: Experimental hematology, Vol. 28, Issue 6, pp. 690-9, (2000) (PubMed).

    Fluckiger, Sanz, Garcia-Lloret, Su, Hao, Kato, Quan, de la Hera, Crooks, Witte, Rawlings: "In vitro reconstitution of human B-cell ontogeny: from CD34(+) multipotent progenitors to Ig-secreting cells." in: Blood, Vol. 92, Issue 12, pp. 4509-20, (1999) (PubMed).

    Janowska-Wieczorek, Marquez, Nabholtz, Cabuhat, Montaño, Chang, Rozmus, Russell, Edwards, Turner: "Growth factors and cytokines upregulate gelatinase expression in bone marrow CD34(+) cells and their transmigration through reconstituted basement membrane." in: Blood, Vol. 93, Issue 10, pp. 3379-90, (1999) (PubMed).

  • Target
    CD34
    Andere Bezeichnung
    CD34 (CD34 Produkte)
    Synonyme
    AU040960 antikoerper, CD34 molecule antikoerper, CD34 antigen antikoerper, CD34 antikoerper, Cd34 antikoerper
    Hintergrund
    CD34 Molecule,CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
    Gen-ID
    947
    UniProt
    P28906
Sie sind hier:
Kundenservice