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BIRC3 Antikörper (Internal Region)
BIRC3
Reaktivität: Human, Ratte
WB, EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-BIRC3 Antikörper
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Target
Alle BIRC3 Antikörper anzeigen
BIRC3
(Baculoviral IAP Repeat Containing 3 (BIRC3))
Bindungsspezifität
Alle Epitope für BIRC3 Antikörper
Internal Region
Reaktivität
Alle Reaktivitäten für BIRC3 Antikörper
Human, Ratte
Wirt
Alle Wirte für BIRC3 Antikörper
Ziege
Klonalität
Alle Klonalitäten für BIRC3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für BIRC3 Antikörper
Dieser BIRC3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BIRC3 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequenz
C-SVNNLEATSQ P
Spezifität
Recognizes BIRC3.
Kreuzreaktivität (Details)
Species reactivity (expected):Human. Species reactivity (tested):Rat.
Aufreinigung
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_001156.1. Genename: BIRC3
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Discover our top product BIRC3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
Reported variants represent identical protein: NP_892007.1, NP_001156.1.
Konzentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu BIRC3
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Target
BIRC3
(Baculoviral IAP Repeat Containing 3 (BIRC3))
Andere Bezeichnung
IAP1 / BIRC3 (BIRC3 Produkte )
Synonyme
AIP1 antikoerper, API2 antikoerper, CIAP2 antikoerper, HAIP1 antikoerper, HIAP1 antikoerper, MALT2 antikoerper, MIHC antikoerper, RNF49 antikoerper, c-IAP2 antikoerper, Api1 antikoerper, Api2 antikoerper, IAP1 antikoerper, IAP2 antikoerper, MIHB antikoerper, Birc2 antikoerper, HIAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, cIAP1 antikoerper, cIAP2 antikoerper, cIAP-1 antikoerper, cIAP-2 antikoerper, AW107670 antikoerper, BIRC2 antikoerper, baculoviral IAP repeat containing 3 antikoerper, baculoviral IAP repeat-containing 3 antikoerper, baculoviral IAP repeat-containing protein 3 antikoerper, inhibitor of apoptosis protein-2 antikoerper, BIRC3 antikoerper, Birc3 antikoerper, LOC100399118 antikoerper, OpmnVgp074 antikoerper
Hintergrund
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.Synonyms: API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, HIAP-1, IAP homolog C, Inhibitor of apoptosis protein 1, MIHC, RING finger protein 49, RNF49, TNFR2-TRAF-signaling complex protein 1, cIAP2
Gen-ID
330
NCBI Accession
NP_001156
UniProt
Q13489
Pathways
Apoptose , Caspase Kaskade in der Apoptose , Activation of Innate immune Response , Toll-Like Receptors Cascades
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