Butyrylcholinesterase Antikörper
Kurzübersicht für Butyrylcholinesterase Antikörper (ABIN568155)
Target
Alle Butyrylcholinesterase (BCHE) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The antibody recognizes Butyrylcholinesterase from Human Serum. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
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Aufreinigung
- Solid Phase Affinity Chromatography
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Immunogen
- Butyrylcholinesterase isolated and purified from Human serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore by adding 0.5 mL of sterile distilled water, Prepare working dilutions by adding sterile phosphate buffered saline (PBS, ph 7.2) and preferably use the same day.
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Konzentration
- 2.0 mg/mL
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Buffer
- PBS, pH 7.2 stabilized with Dextran, without preservatives and foreign proteins
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody lyophilized at 2-8 °C Reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
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- Butyrylcholinesterase (BCHE)
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Andere Bezeichnung
- Cholinesterase
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Hintergrund
- Butyrylcholinesterase is synthetizised in the liver, and is predominantly found in serum, liver and pancreas. This enzyme is a tetrameric glycoprotein (molecular mass of 350 kDa), and consists of four subunits. Defects in Butyrylcholinesterase are the cause of a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics.Synonyms: Acylcholine acylhydrolase, BCHE, Butyrylcholine esterase, CHE1, Choline esterase II, Pseudocholinesterase
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Gen-ID
- 590
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NCBI Accession
- NP_000046
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UniProt
- P06276
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Pathways
- Peptide Hormone Metabolism
Target
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