NEDD1 Antikörper (AA 561-660)

Produktnummer ABIN566771

Produktdetails anti-NEDD1 Antikörper

Target: NEDD1 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1))

Bindungsspezifität: AA 561-660

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NEDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant NEDD1.

Sequenz: AGVASSLSEK IADSIGNNRQ NAPLTSIQIR FIQNMIQETL DDFREACHRD IVNLQVEMIK QFHMQLNEMH SLLERYSVNE GLVAEIERLR EENKRLRAHF

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: NEDD1 (NP_690869, 561 a.a. ~ 660 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 7D10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-NEDD1 Antikörper (ABIN566771)

Uehara, Kamasaki, Hiruma, Poser, Yoda, Yajima, Gerlich, Goshima: "Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission." in: Molecular biology of the cell, Vol. 27, Issue 5, pp. 812-27, (2016) (PubMed).

Lecland, Lüders: "The dynamics of microtubule minus ends in the human mitotic spindle." in: Nature cell biology, Vol. 16, Issue 8, pp. 770-8, (2014) (PubMed).

Stiess, Maghelli, Kapitein, Gomis-Rüth, Wilsch-Bräuninger, Hoogenraad, Toli?-Nørrelykke, Bradke: "Axon extension occurs independently of centrosomal microtubule nucleation." in: Science (New York, N.Y.), Vol. 327, Issue 5966, pp. 704-7, (2010) (PubMed).

Archinti, Lacasa, Teixidó-Travesa, Lüders: "SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression." in: Journal of cell science, Vol. 123, Issue Pt 18, pp. 3039-46, (2010) (PubMed).

Uehara, Goshima: "Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 259-67, (2010) (PubMed).

Teixidó-Travesa, Villén, Lacasa, Bertran, Archinti, Gygi, Caelles, Roig, Lüders: "The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8." in: Molecular biology of the cell, Vol. 21, Issue 22, pp. 3963-72, (2010) (PubMed).

Haren, Stearns, Lüders: "Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components." in: PLoS ONE, Vol. 4, Issue 6, pp. e5976, (2009) (PubMed).

Zhu, Fang, Fang: "FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes." in: Journal of cell science, Vol. 122, Issue Pt 15, pp. 2750-9, (2009) (PubMed).

Zhu, Coppinger, Jang, Yates, Fang: "FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle." in: The Journal of cell biology, Vol. 183, Issue 5, pp. 835-48, (2008) (PubMed).

Details zu NEDD1

Target: NEDD1 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1))

Andere Bezeichnung: NEDD1 (NEDD1 Produkte)

Synonyme: MGC81767 antikoerper, MGC145237 antikoerper, GCP-WD antikoerper, TUBGCP7 antikoerper, neural precursor cell expressed, developmentally down-regulated 1 L homeolog antikoerper, neural precursor cell expressed, developmentally down-regulated 1 antikoerper, cilia and flagella associated protein 54 antikoerper, neural precursor cell expressed, developmentally down-regulated gene 1 antikoerper, nedd1.L antikoerper, nedd1 antikoerper, CFAP54 antikoerper, NEDD1 antikoerper, Nedd1 antikoerper

Hintergrund: Full Gene Name: neural precursor cell expressed, developmentally down-regulated 1
Synonyms: FLJ35902,GCP-WD,TUBGCP7

Gen-ID: 121441

NCBI Accession: NM_152905

Pathways: M Phase