HERC5 Antikörper (AA 915-1024)

Produktnummer ABIN565561

Produktdetails anti-HERC5 Antikörper

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Bindungsspezifität: AA 915-1024

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser HERC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse polyclonal antibody raised against a partial recombinant HERC5.

Sequenz: YDWKTFEKNA RYEPGYNSSH PTIVMFWKAF HKLTLEEKKK FLVFLTGTDR LQMKDLNNMK ITFCCPESWN ERDPIRALTC FSVLFLPKYS TMETVEEALQ EAINNNRGFG

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: HERC5 (NP_057407, 915 a.a. ~ 1024 a.a) partial recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HERC5 Antikörper (ABIN565561)

Im, Yoo, Hyun, Shin, Chung: "Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin." in: Open biology, Vol. 6, Issue 8, (2016) (PubMed).

Park, Yoon, Kim, Kim: "90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus." in: Neoplasia (New York, N.Y.), Vol. 18, Issue 10, pp. 618-625, (2016) (PubMed).

Woods, Tong, Tom, Szabo, Cavanagh, Dikeakos, Haeryfar, Barr: "Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export." in: Retrovirology, Vol. 11, pp. 27, (2014) (PubMed).

Woods, Kelly, Hattlmann, Tong, Xu, Coleman, Quest, Smiley, Barr: "Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag." in: Retrovirology, Vol. 8, pp. 95, (2011) (PubMed).

Details zu HERC5

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Andere Bezeichnung: HERC5 (HERC5 Produkte)

Synonyme: HERC5 antikoerper, CEB1 antikoerper, CEBP1 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antikoerper, hect domain and RLD 5 antikoerper, HERC5 antikoerper

Hintergrund: Full Gene Name: hect domain and RLD 5
Synonyms: CEB1,CEBP1

Gen-ID: 51191

NCBI Accession: NM_016323