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NOTCH3 Antikörper (AA 47-156)

NOTCH3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1G5 unconjugated
Produktnummer ABIN562028
  • Target Alle NOTCH3 Antikörper anzeigen
    NOTCH3 (Notch 3 (NOTCH3))
    Bindungsspezifität
    • 19
    • 11
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 47-156
    Reaktivität
    • 58
    • 17
    • 11
    • 1
    Human
    Wirt
    • 39
    • 19
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 43
    • 21
    Monoklonal
    Konjugat
    • 32
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NOTCH3 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 27
    • 25
    • 12
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Verwendungszweck
    Mouse monoclonal antibody raised against a partial recombinant NOTCH3.
    Sequenz
    SPCANGGRCT QLPSREAACL CPPGWVGERC QLEDPCHSGP CAGRGVCQSS VVAGTARFSC RCPRGFRGPD CSLPDPCLSS PCAHGARCSV GPDGRFLCSC PPGYQGRSCR
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    1G5
    Isotyp
    IgG2a
    Top Product
    Discover our top product NOTCH3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

    Watanabe-Hosomi, Watanabe, Tanaka, Nakagawa, Mizuno: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).

    Tada, Itoh, Ishii-Watabe, Suzuki, Kawasaki: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).

    Dong, Blaivas, Wang: "Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy." in: Brain research, Vol. 1456, pp. 64-71, (2012) (PubMed).

    Lee, Meng, Elmadhoun, Blaivas, Wang: "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication." in: Archives of neurology, Vol. 68, Issue 12, pp. 1584-6, (2011) (PubMed).

    Meng, Zhang, Hankenson, Wang: "Thrombospondin 2 potentiates notch3/jagged1 signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7866-74, (2009) (PubMed).

    Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).

  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Andere Bezeichnung
    NOTCH3 (NOTCH3 Produkte)
    Synonyme
    CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper
    Hintergrund
    Full Gene Name: Notch homolog 3 (Drosophila)
    Synonyms: CADASIL,CASIL
    Gen-ID
    4854
    NCBI Accession
    NM_000435
    Pathways
    Notch Signalweg
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