MAD2L1 Antikörper (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 3-13)

Details for Product anti-MAD2L1 Antibody No. ABIN5556684, Anbieter: Anmelden zum Anzeigen
Antigen
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
Epitop
AA 3-13
19
8
6
6
4
4
4
3
3
3
2
2
1
1
1
1
1
1
Reaktivität
Human
120
36
33
9
6
5
4
4
4
3
3
2
2
1
Wirt
Kaninchen
71
34
15
1
Klonalität
Polyklonal
Konjugat
Dieser MAD2L1 Antikörper ist unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
102
46
23
22
21
20
13
6
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Dieses Produkt umsonst

Schicken Sie uns Ihren Validierungsvorschlag. Ich möchte dieses Produkt validieren

Mehr erfahren

Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues 3-13 of Human MAD2L1 protein.
Sequenz Human MAD2L1, 205 amino acids, predicated MW 23.5 kDa. 1 malqlsreqg itlrgsaeiv aeffsfgins ilyqrgiyps etftrvqkyg ltllvttdle 61 likylnnvve qlkdwlykcs vqklvvvisn iesgevlerw qfdiecdkta kddsapreks 121 qkaiqdeirs virqitatvt flpllevscs fdlliytdkd lvvpekwees gpqfitnsee 181 vrlrsfttti hkvnsmvayk ipvnd
Spezifität This affinity purified antibody is directed against human MAD2L1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, dog, macaque, chimpanzee and gecko based on 100 % homology for the immunogen sequence. Cross reactivity with MAD2L1 may occur from mouse and chicken sources, as only a two amino acid residue change is found within the immunogen sequence (90 % positive by BLAST). Cross reactivity with MAD2L1 homologues from other sources has not been determined.
Produktmerkmale Concentration: 1.19 mg/mL (by UV absorbance at 280 nm)
Reinigung Immunoaffinity chromatography.
Andere Bezeichnung MAD2L1 (MAD2L1 Antibody Abstract)
Hintergrund MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A
Gen-ID 4085
NCBI Accession NP_002349
UniProt Q13257
Forschungsgebiet Cell Cycle
Applikationshinweise This affinity purified antibody has been tested for use in ELISA (1: 2,000-1: 10,000) and byWestern blot (1: 500-1: 2,000). Specific conditions for reactivity should be optimized by theend user. Expect a predominant band at approx. 24 kDa corresponding to full length protein bywestern blotting in the appropriate cell lysate or extract.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.19 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung This product is photosensitive and should be protected from light
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 2-8 °C. DO NOT FREEZE!