MTF1 Antikörper (C-Term)

Produktnummer ABIN1108308

Produktdetails anti-MTF1 Antikörper

Target: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Hund, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG

Kreuzreaktivität (Details): Species reactivity (expected):Mouse (100 %), Rat (100 %), Dog (100 %), Bovine (100 %), Horse (100 %), Guinea Pig (92 %), Rabbit (92 %).
Species reactivity (tested):Human.

Aufreinigung: Purified on Protein A affinity column.

Immunogen: The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Haltbarkeit: 12 months

Details zu MTF1

Target: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Andere Bezeichnung: MTF1 (MTF1 Produkte)

Synonyme: MTF-1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, MGC86485 antikoerper, Thyls antikoerper, ZRF antikoerper, metal regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 antikoerper, metal-regulatory transcription factor 1 L homeolog antikoerper, metal response element binding transcription factor 1 antikoerper, MTF1 antikoerper, mtf1 antikoerper, mtf1.L antikoerper, Mtf1 antikoerper

Hintergrund: The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.Synonyms: MRE-binding transcription factor, Metal regulatory transcription factor 1, Transcription factor MTF-1

Molekulargewicht: 81 kDa (753 amino acids)

Gen-ID: 4520

NCBI Accession: NP_005946