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Stim2 Antikörper (Center)

Stim2 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500831
  • Target Alle Stim2 Antikörper anzeigen
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 38
    • 14
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 36
    • 1
    • 1
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 3
    • 2
    • 2
    Dieser Stim2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 27
    • 19
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects STIM2 at center. It is predicted to have no cross-reactivity to STIM1.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    STIM2 antibody was raised against a 17 amino acid peptide from near the center of human STIM2.
    Isotyp
    IgG
    Top Product
    Discover our top product Stim2 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Andere Bezeichnung
    STIM2 (Stim2 Produkte)
    Synonyme
    STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper
    Hintergrund
    In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.Synonyms: KIAA1482, Stromal interaction molecule 2
    Gen-ID
    57620
    NCBI Accession
    NP_065911
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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