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SLPI Antikörper (Center)

SLPI Reaktivität: Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500776
  • Target Alle SLPI Antikörper anzeigen
    SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 48
    • 10
    Maus
    Wirt
    • 39
    • 12
    • 3
    Kaninchen
    Klonalität
    • 43
    • 11
    Polyklonal
    Konjugat
    • 24
    • 11
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLPI Antikörper ist unkonjugiert
    Applikation
    • 43
    • 24
    • 16
    • 12
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Antileukoproteinase (ALP).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    SLPI antibody was raised against a 17 amino acid peptide from near the center of mouse SLPI.
    Isotyp
    IgG
    Top Product
    Discover our top product SLPI Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
    Andere Bezeichnung
    Antileukoproteinase (ALP) (SLPI Produkte)
    Synonyme
    ALK1 antikoerper, ALP antikoerper, BLPI antikoerper, HUSI antikoerper, HUSI-I antikoerper, MPI antikoerper, WAP4 antikoerper, WFDC4 antikoerper, MATN4 antikoerper, SLPI antikoerper, ckpi antikoerper, secretory leukocyte peptidase inhibitor antikoerper, antileukoproteinase antikoerper, SLPI antikoerper, Slpi antikoerper, LOC102174044 antikoerper
    Hintergrund
    Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kB activation by inhibiting IkB degradation in the cytoplasm and competing for NF-kB binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4
    Gen-ID
    20568
    NCBI Accession
    NP_035544
    UniProt
    P97430
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