SLITRK1 Antikörper (C-Term)

Produktnummer ABIN500750

Produktdetails anti-SLITRK1 Antikörper

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Bindungsspezifität: C-Term

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SLITRK1 at C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Huamn, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Slitrk1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SLITRK1

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Andere Bezeichnung: SLITRK1 (SLITRK1 Produkte)

Synonyme: DKFZp459G0529 antikoerper, LRRC12 antikoerper, TTM antikoerper, 3200001I04Rik antikoerper, SLIT and NTRK like family member 1 antikoerper, SLIT and NTRK-like family, member 1 antikoerper, SLITRK1 antikoerper, slitrk1 antikoerper, Slitrk1 antikoerper

Hintergrund: SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.Synonyms: KIAA1910, LRRC12, Leucine-rich repeat-containing protein 12, SLIT and NTRK-like protein 1

Gen-ID: 114798

NCBI Accession: NP_443142

UniProt: Q96PX8