MYBPC2 Antikörper (C-Term)

Produktnummer ABIN500298

Produktdetails anti-MYBPC2 Antikörper

Target: MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Referenzen für anti-MYBPC2 Antikörper (ABIN500298)

Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).

Details zu MYBPC2

Target: MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))

Andere Bezeichnung: MYBPC2 (MYBPC2 Produkte)

Synonyme: MYBPC antikoerper, MYBPCF antikoerper, im:7137115 antikoerper, im:7150089 antikoerper, zgc:110761 antikoerper, myosin binding protein C, fast-type antikoerper, myosin binding protein C, fast type antikoerper, myosin-binding protein C, fast-type antikoerper, myosin binding protein C, fast type b antikoerper, Mybpc2 antikoerper, MYBPC2 antikoerper, LOC520988 antikoerper, mybpc2b antikoerper

Hintergrund: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.Synonyms: C-protein, Fast MyBP-C, MYBPCF, Myosin-binding protein C, skeletal muscle fast isoform

Gen-ID: 4606

NCBI Accession: NP_004524

UniProt: Q14324