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CD82 Antikörper (C-Term)

CD82 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500108
  • Target Alle CD82 Antikörper anzeigen
    CD82
    Bindungsspezifität
    • 15
    • 13
    • 13
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 65
    • 36
    • 5
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 58
    • 29
    Kaninchen
    Klonalität
    • 57
    • 30
    Polyklonal
    Konjugat
    • 30
    • 10
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD82 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 39
    • 28
    • 23
    • 20
    • 18
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects CD82 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    KAI1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human KAI1.
    Isotyp
    IgG
    Top Product
    Discover our top product CD82 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CD82
    Andere Bezeichnung
    CD82 (CD82 Produkte)
    Synonyme
    AA682076 antikoerper, AL023070 antikoerper, C33 antikoerper, IA4 antikoerper, Kai1 antikoerper, Tspan27 antikoerper, 4F9 antikoerper, GR15 antikoerper, KAI1 antikoerper, R2 antikoerper, SAR2 antikoerper, ST6 antikoerper, TSPAN27 antikoerper, CD82 antigen antikoerper, CD82 molecule antikoerper, Cd82 molecule antikoerper, Cd82 antikoerper, CD82 antikoerper
    Hintergrund
    KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.Synonyms: C33 antigen, IA4, Inducible membrane protein R2, KAI1, Kangai-1, Metastasis suppressor Kangai-1, SAR2, ST6, Suppressor of tumorigenicity protein 6, TSPAN27, Tetraspanin-27
    Gen-ID
    3732
    NCBI Accession
    NP_002222
    UniProt
    P27701
    Pathways
    p53 Signalweg
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