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GFRA1 Antikörper (Intermediate Domain)

GFRA1 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499883
  • Target Alle GFRA1 Antikörper anzeigen
    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
    Bindungsspezifität
    • 16
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intermediate Domain
    Reaktivität
    • 55
    • 36
    • 18
    • 16
    Human, Maus, Ratte
    Wirt
    • 49
    • 6
    • 2
    Kaninchen
    Klonalität
    • 51
    • 6
    Polyklonal
    Konjugat
    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GFRA1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 16
    • 15
    • 13
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    GFR alpha 1 antibody was raised against a peptide corresponding to amino acids 369 to 382 of human GFR alpha 1.
    Aufreinigung
    DEAE Chromatography
    Immunogen
    Human GFR alpha 1 (Intermediate Domain) Peptide
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    ELISA. Western Blot. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
    Andere Bezeichnung
    GFRA1 / GDNFR-alpha (GFRA1 Produkte)
    Synonyme
    gdnfr antikoerper, ret1l antikoerper, retl1 antikoerper, trnr1 antikoerper, gdnfra antikoerper, MGC122616 antikoerper, gfr-alpha-1 antikoerper, GDNFR antikoerper, GDNFRA antikoerper, GFR-ALPHA-1 antikoerper, RET1L antikoerper, RETL1 antikoerper, TRNR1 antikoerper, GDNFRALPHA antikoerper, GFRA1 antikoerper, AU042498 antikoerper, gfralpha1a antikoerper, zgc:110129 antikoerper, GDNF family receptor alpha 1 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 1 antikoerper, gdnf family receptor alpha 1a antikoerper, gfra1 antikoerper, GFRA1 antikoerper, Gfra1 antikoerper, gfra1a antikoerper
    Hintergrund
    Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently. GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.Synonyms: GDNF family receptor alpha-1, GDNF receptor alpha, GDNFRA, GFR-alpha-1, RET ligand 1, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1
    Gen-ID
    2674
    UniProt
    P56159
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