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APC1 Antikörper (C-Term)

ANAPC1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499291
  • Target Alle APC1 (ANAPC1) Antikörper anzeigen
    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
    Bindungsspezifität
    • 26
    • 16
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 49
    • 39
    • 24
    Human, Maus
    Wirt
    • 79
    • 1
    Kaninchen
    Klonalität
    • 79
    • 1
    Polyklonal
    Konjugat
    • 31
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser APC1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 40
    • 32
    • 14
    • 14
    • 13
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    APC1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human APC1.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: APC1 antibody can be used for detection of APC1 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
    Andere Bezeichnung
    APC1 / ANAPC1 (ANAPC1 Produkte)
    Synonyme
    APC1 antikoerper, MCPR antikoerper, TSG24 antikoerper, DDBDRAFT_0186456 antikoerper, DDBDRAFT_0234263 antikoerper, DDB_0186456 antikoerper, DDB_0234263 antikoerper, 2610021O03Rik antikoerper, AI047775 antikoerper, AI853536 antikoerper, AW547281 antikoerper, Apc1 antikoerper, Mcpr antikoerper, tsg24 antikoerper, EMBRYO DEFECTIVE 2771 antikoerper, MOP10.10 antikoerper, MOP10_10 antikoerper, anaphase promoting complex subunit 1 antikoerper, E3 ubiquitin ligase antikoerper, ANAPC1 antikoerper, Anapc1 antikoerper, CC1G_09696 antikoerper, anapc1 antikoerper, EMB2771 antikoerper
    Hintergrund
    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein
    Gen-ID
    64682
    UniProt
    Q9H1A4
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