MFSD2A Antikörper (C-Term)

Produktnummer ABIN783763

Produktdetails anti-MFSD2A Antikörper

Target: MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFSD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects MFSD2 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human MFSD2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu MFSD2A

Target: MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))

Andere Bezeichnung: MFSD2 (MFSD2A Produkte)

Synonyme: 1700018O18Rik antikoerper, Mfsd2 antikoerper, RGD1310174 antikoerper, MFSD2 antikoerper, NLS1-A antikoerper, Sodium-dependent LPC symporter 1-A antikoerper, mfsd2a antikoerper, zgc:101615 antikoerper, mfsd2 antikoerper, NLS1-B antikoerper, Sodium-dependent LPC symporter 1-B antikoerper, mfsd2b antikoerper, zgc:101069 antikoerper, major facilitator superfamily domain containing 2A antikoerper, major facilitator superfamily domain containing 2aa antikoerper, major facilitator superfamily domain containing 2A L homeolog antikoerper, major facilitator superfamily domain containing 2ab antikoerper, MFSD2A antikoerper, mfsd2a antikoerper, Mfsd2a antikoerper, mfsd2aa antikoerper, mfsd2a.L antikoerper, mfsd2ab antikoerper

Hintergrund: Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.Synonyms: HMFN0656, Major facilitator superfamily domain-containing protein 2, PP9177

Gen-ID: 84879

NCBI Accession: NP_001129965

UniProt: Q8NA29