Calneuron 1 Antikörper (N-Term)

Produktnummer ABIN783669

Produktdetails anti-Calneuron 1 Antikörper

Target: Calneuron 1 (CALN1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calneuron 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human CaBP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu Calneuron 1

Target: Calneuron 1 (CALN1)

Andere Bezeichnung: Calneuron-1 (CALN1 Produkte)

Synonyme: CALN1 antikoerper, CABP8 antikoerper, 9630012C17Rik antikoerper, Cabp8 antikoerper, calneuron 1 antikoerper, CALN1 antikoerper, caln1 antikoerper, Caln1 antikoerper

Hintergrund: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP7 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.Synonyms: CABP8, CALN1, Calcium-binding protein CaBP8

Gen-ID: 83698

NCBI Accession: NP_001017440

UniProt: Q9BXU9