P5CS Antikörper (C-Term)

Produktnummer ABIN569586

Produktdetails anti-P5CS Antikörper

Target: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser P5CS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-SEHGSLKYLH

Spezifität: This antibody is expected to recognize both reported isoforms of ALDH18A1 (NP_002851.2, NP_001017423.1).

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Canine (Dog), Cow, Pig.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_002851.2, NP_001017423.1. Genename: ALDH18A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu P5CS

Target: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Andere Bezeichnung: ALDH18A1 (ALDH18A1 Produkte)

Synonyme: ALDH18A1 antikoerper, ARCL3A antikoerper, GSAS antikoerper, P5CS antikoerper, PYCS antikoerper, 2810433K04Rik antikoerper, AI429789 antikoerper, Pycs antikoerper, cb842 antikoerper, cb899 antikoerper, pycs antikoerper, sb:cb881 antikoerper, wu:fa91f10 antikoerper, wu:fi05f11 antikoerper, wu:fi17d12 antikoerper, aldehyde dehydrogenase 18 family member A1 antikoerper, aldehyde dehydrogenase 18 family, member A1 antikoerper, aldehyde dehydrogenase 18 family member A1 L homeolog antikoerper, ALDH18A1 antikoerper, aldh18a1 antikoerper, Aldh18a1 antikoerper, aldh18a1.L antikoerper

Hintergrund: Defects in ALDH18A1 are the cause of mental retardation-joint hypermobility-skin laxity with or without metabolic abnormalities (MRJHSL) [MIM:612652]. Clinical manifestations include microcephaly, progressive neurologic dysfunction, mental retardation, progeroid appearance, joint hypermobility, skin laxity and hyperelasticity, cataracts. Some patients manifest metabolic disturbances such as hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia.Synonyms: Aldehyde dehydrogenase family 18 member A1, Delta-1-pyrroline-5-carboxylate synthetase, GSAS, P5CS, PYCS

Molekulargewicht: 87.3kDa (NP_002851.2).

Gen-ID: 5832

NCBI Accession: NP_001017423

UniProt: P54886